The Drive with Peter Attia — Matt Kaeberlein

On: Rapamycin and dogs — man’s best friends? Episode: 10 Date: August 2018 Key Subjects: Involved in dog ageing research project:Live in similar environment as humans.Die from similar diseases as humans (although cancer is the most common in dogs, versus

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The Drive with Peter Attia — David Sabatini

On: Rapamycin and the discovery of mTOR — the nexus of aging and longevity? Episode: 9 Date: August 2018 Key Subjects: mTOR (mammalian target of rapamycin) (see mTOR write-up) Central regulator of metabolism and physiology. Regulating many cellular processes (cell

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mTOR

Summary Introduction. mTOR Activation and Inhibition. Rapamycin. Sources. Introduction Mammalian target of rapamycin (mTOR). Involved in cell metabolism, survival, and growth Central regulator of metabolism and physiology. Regulates many cellular processes. Ccell growth, proliferation, protein synthesis, autophagy. Within the cell,

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