Summary Introduction. mTOR Activation and Inhibition. Rapamycin. Sources. Introduction Mammalian target of rapamycin (mTOR). Involved in cell metabolism, survival, and growth Central regulator of metabolism and physiology. Regulates many cellular processes. Ccell growth, proliferation, protein synthesis, autophagy. Within the cell,
Summary Introduction. How Insulin May Affect SHBG. How SHBG Affects Free versus Bound Sex Hormones. Impact of Low SHBG. Impact of High SHBG. How to Increase SHBG (When it’s Too Low). How to Reduce SHBG (When it’s Too High). Causes
Summary Introduction. Causes of Senescent Cells. Process of Senescent Cells Generation. Senescence-Associated Secretory Phenotype (SASP). Effect of Build-up of Senescent Cells. mTOR and Senescence. Role of Telomeres. Potential Fixes. Sources and Links. Introduction Normal cells cease to divide. Maximum of approximately
Summary: Sauna helps to induce hypertrophy (increase in size of muscle cells). Oxidative stress (through exercise) is a source of protein degradation. Heat acclimation reduces protein degradation (and stimulates hypertrophy) through: Induction of heat shock proteins. Induction of growth hormones.
Avoid or do less. Constant feeding… What to do. Routinely: Time restricted feeding most interesting and practical (“FoundMyFitness — Satchin Panda“) Squeeze three meals into relatively short time period. Late breakfast, normal lunch, early dinner. Align with circadian rhythm. Provide