On: Slowing aging – sirtuins, NAD, and the epigenetics of aging Episode: 27 Date: November 2018 Key Subjects: Genetics professor at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. Sirtuins. Play a
How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance By: Nessa Carey Published: 2012 Read: 2018 Summary: Epigenetics refers to external modifications of DNA that regulate the expression of genes, turning them “on” or “off.” While the
Summary Introduction. Saturated Fatty Acids. Unsaturated Fatty Acids. MUFA — Omega-9. PUFA — Omega-3. PUFA — Omega-6. Omega-6 to Omega-3 Ratio. Lower Omega-6. Moderately Increase Omega-3. Supplement GLA. Supplement Curcumin. Role in Early Life. Introduction Fats. One of the five
Summary Introduction. Sirtuins and Gene Silencing. Sirtuins Activity. Sirtuins and Senescence. Introduction Silent information regulator (SIR). Crossroads of nutrient sensing and stress regulation. Responds to energy and nutrients. Controls cellular health. Regulates adaptive response to energy availability. Silences genes. Repairs
Energy, Evolution, and the Origins of Complex Life. By: Nick Lane Published: 2015 Read: 2019 Summary: Why is life the way it is. Complex life on earth probably arose once only from a single common ancestor. We don’t know how
The greatest espionage story of the cold war. By: Ben Macintyre Published: 2018 Read: 2019 Summary: As the Cold War heats up, Oleg Gordievsky, a KGB agent, becomes disappointed with the brutalities of the Soviet system, develops an appreciation of
Secrets and lies in a Silicon Valley startup. By: John Carreyrou Published: 2018 Read: 2019 Summary: The rise and fall of Theranos, a Silicon Valley startup that tried unsuccessfully to develop a miniature blood testing device. Pursuing a “fake-it-till-you-make-it approach”,
On: Navigating the many pathways to health and disease Episode: 46 Date: March 2019 Key Subjects: Entrepreneur, independent researcher and doctorate in nutrition. Methylation. See Methylation write-up for more details. Methylation cycle: From methionine to homocysteine. Homocysteine either gets broken
The topic of NAD comes up in multiple episodes of the The Drive with Peter Attia, including David Sinclair and Chris Masterjohn. This summary is based partly on those conversations, as well as other public source material. This is a
This summary was put together based on a wide variety of public information, much of it from Wikipedia. Certain sections of the summary below borrow heavily from the podcast “The Drive with Peter Attia — Chris Masterjohn“ where methylation is