Summary Stress: adaptive response to situations that pose demands, constraints or opportunities. Homeostasis: low stress. Stressors challenge homeostasis: stress response. Return to homeostasis: recovery, return to low stress. Or inability to return to homeostasis: exhaustion, chronic stress. Stressors: wide variety.
Breathing: (“The Oxygen Advantage“) Exercise lowers oxygen (hypoxia) and increases CO2 (hypercapnia). Oxygen needs to supplied (by breathing in). CO2 needs to be removed (by breathing out). The level of CO2 in your body drives both the intake and uptake
Avoid or do less. Reduce harm by removing things, rather than adding to it. May not make sense to add supplements: Figure out. Measure, test to identify specific (genetic) requirements (see “Tests“). Determine proper brand of supplement (reputation, ingredients, etc.).
Three forms of nutrition restriction. Time restriction (when you eat). Caloric restriction (how much you eat). Diet restriction (what you eat). Crude approach Technical macro-nutrients approach. (“FoundMyFitness — Peter Attia“) Proteins: up to level needed to maintain muscle mass. Carbs:
Three forms of nutrition restriction. Time restriction (when you eat). Caloric restriction (how much you eat). Diet restriction (what you eat). Figure out what type of foods to avoid or do less of. Fructose – moderate (dose control). (“Nutrition —
Master regulator of metabolism. Restores energy balance during metabolic stress. Activated by depletion in ATP supplies. Low glucose, heat shock, and other energy stresses. ATP -> donates phosphor -> ADP -> donates phosphor -> AMP. Energy stresses show up as
Key Takeaways: Fructose and glucose are very similar simple carbohydrates. Fructose is found in fruits and vegetables. Glucose is made by plants, mostly consumed in bonded form (lactose, starch, etc.). Fructose and glucose play a role in the storage and
By: Ole Peters and Alexander Adamou In: Lecture notes and blog posts Date: 2019 Introduction The lecture notes and blog posts introduce and develop ergodicity theory, in the process challenging the foundations of economic theory, as well as providing mathematical
Summary Introduction. Ageing and disease. Nine Hallmarks of Ageing. Genomic Instability. Telomere Attrition. Epigenetic Alterations. Cellular Senescence. Deregulated Nutrient Sensing Mitochondrial Dysfunction. Stem Cell Exhaustion. Loss of Proteostasis. Altered Intercellular Communication. Ageing and Cognitive Diseases. Ageing and Dietary Restriction (DR).
Summary Introduction. Saturated Fatty Acids. Unsaturated Fatty Acids. MUFA — Omega-9. PUFA — Omega-3. PUFA — Omega-6. Omega-6 to Omega-3 Ratio. Lower Omega-6. Moderately Increase Omega-3. Supplement GLA. Supplement Curcumin. Role in Early Life. Introduction Fats. One of the five